Abstract: With the continuous opening of my country’s low-altitude airspace, the low-altitude flight safety and weather protection system is being valued by more and more researchers.The development of the UAV industry in the Beijing-Tianjin-Hebei region is in a leading position in China.Based on the WRF (Weather Research and Forecasting Model) mesoscale numerical model, this paper simulates the meteorological elements in the Beijing-Tianjin-Hebei region from 2015 to 2019, and the error comparison analysis between the simulation results and the observation data of the weather station, can provide suggestions for the flight safety of UAV low-altitude routes in the region.Combining the UAV flight restriction factors, analyze the average distribution and vertical average distribution of meteorological elements on UAV routes in the Beijing-Tianjin-Hebei region, the conclusions are as follows:(1) The wind speed above 5.5 m/s appears in the Baishi Mountain to Dongling Mountain in winter, spring and autumn, which can cause violent shaking or even blow up the drone during the flight.You should always pay attention to flying in this area.Wind speed changes.(2) In winter, the entire Beijing-Tianjin-Hebei region is controlled at 0 ℃ and below 0 ℃, due to temperature conditions, it is not suitable for drones to fly, and the temperature range in other seasons is within the normal operating range of drone batteries.(3) In summer, the Beijing-Tianjin-Hebei region receives heavy rainfall, and attention should be paid to the impact of heavy rainfall on UAV flight.(4) Vertically, in the low-altitude airspace, wind speeds in winter, spring and autumn will affect the flight of UAVs.Winter temperatures below 0 ℃ are not suitable for low-altitude operations.