Abstract: In China, Civil UAV operation has been used in a variety of fields, such as film and television, agriculture and forestry, survey and security. The operation altitude of UAV operation is mostly in low altitude airspace, which belongs to the application branch of general aviation (GA) field. As one of the most important basic guarantees of UAV operation, meteorological services have increasingly become a bottleneck restricting the development of China’s GA industry. Currently there is a lack of systematic and targeted meteorological indicators and support measures. Based on UAV application fields, meteorological influencing factors and the formulation of UAV operation meteorological standards, this paper puts forward the idea of “multi-sectoral cooperation”to build the UAV operation meteorological index system. The plant protection operation is taken as an example, and both the weather information record and the weather forecast record for UAV plant protection operation are provided references for the development of meteorological services. Then, the future outlook of meteorological support for UAV operation, which is still insufficient, is proposed from the aspects of meteorological index system construction, multiple data fusion, and the establishment and improvement of communication mechanism. It is hoped that the research results can not only offer some advice and suggestions for the establishment of meteorological support system for UAV operation but also lay the theoretical foundation for expanding new fields and innovative development of GA meteorological services.